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Characterization of cryptic rearrangements, deletion, complex variants of PML, RARA in acute promyelocytic leukemia

Acute promyelocytic leukemia (APL) is characterized by a reciprocal translocation t(15;17)(q22;q21) leading to the disruption of Promyelocytic leukemia (PML) and Retionic Acid Receptor Alpha (RARA) followed by reciprocal PML–RARA fusion in 90% of the cases. Fluorescence in situ hybridization (FISH)...

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Detalles Bibliográficos
Autores principales:	Amare, Pratibha Kadam, Baisane, Chanda, Nair, Reena, Menon, Hari, Banavali, Shripad, Kabre, Sharayu, Gujral, Sumit, Subramaniam, P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214318/ https://www.ncbi.nlm.nih.gov/pubmed/22090713 http://dx.doi.org/10.4103/0971-6866.86174

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