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Asymptomatic falciparum malaria and intestinal helminths co-infection among school children in Osogbo, Nigeria

BACKGROUND: Malaria and intestinal helminths are parasitic diseases causing high morbidity and mortality in most tropical parts of the world, where climatic conditions and sanitation practices favor their prevalence. The aim of this study was to determine the prevalence and possible impact of falcip...

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Autores principales: Ojurongbe, Olusola, Adegbayi, Adebola M, Bolaji, Oloyede S, Akindele, Akeem A, Adefioye, Olusegun A, Adeyeba, Oluwaseyi A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214381/
https://www.ncbi.nlm.nih.gov/pubmed/22091292
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author Ojurongbe, Olusola
Adegbayi, Adebola M
Bolaji, Oloyede S
Akindele, Akeem A
Adefioye, Olusegun A
Adeyeba, Oluwaseyi A
author_facet Ojurongbe, Olusola
Adegbayi, Adebola M
Bolaji, Oloyede S
Akindele, Akeem A
Adefioye, Olusegun A
Adeyeba, Oluwaseyi A
author_sort Ojurongbe, Olusola
collection PubMed
description BACKGROUND: Malaria and intestinal helminths are parasitic diseases causing high morbidity and mortality in most tropical parts of the world, where climatic conditions and sanitation practices favor their prevalence. The aim of this study was to determine the prevalence and possible impact of falciparum malaria and intestinal helminths co-infection among school children in Kajola, Osun state, Nigeria. METHODS: Fresh stool and blood samples were collected from 117 primary school children age range 4-15 years. The stool samples were processed using both Kato-Katz and formol-ether concentration techniques and microscopically examined for intestinal parasitic infections. Blood was collected by finger prick to determine malaria parasitemia using thick film method; and packed cell volume (PCV) was determined by hematocrit. Univariate analysis and chi-square statistical tests were used to analyze the data. RESULTS: The prevalence of Plasmodium falciparum, intestinal helminth infections, and co-infection of malaria and helminth in the study were 25.6%, 40.2% and 4.3%, respectively. Five species of intestinal helminths were recovered from the stool samples and these were Ascaris lumbricoides (34.2%), hookworm (5.1%), Trichuris trichiura (2.6%), Diphyllobothrium latum (0.9%) and Trichostrongylus species (0.9%). For the co-infection of both malaria and intestinal helminths, females (5.9%) were more infected than males (2.0%) but the difference was not statistically significant (p = 0.3978). Children who were infected with helminths were equally likely to be infected with malaria as children without intestinal helminths [Risk Ratio (RR) = 0.7295]. Children with A. lumbricoides (RR = 1.359) were also likely to be infected with P. falciparum as compared with uninfected children. CONCLUSIONS: Asymptomatic falciparum malaria and intestinal helminth infections do co-exist without clinical symp-toms in school children in Nigeria.
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spelling pubmed-32143812011-11-16 Asymptomatic falciparum malaria and intestinal helminths co-infection among school children in Osogbo, Nigeria Ojurongbe, Olusola Adegbayi, Adebola M Bolaji, Oloyede S Akindele, Akeem A Adefioye, Olusegun A Adeyeba, Oluwaseyi A J Res Med Sci Original Article BACKGROUND: Malaria and intestinal helminths are parasitic diseases causing high morbidity and mortality in most tropical parts of the world, where climatic conditions and sanitation practices favor their prevalence. The aim of this study was to determine the prevalence and possible impact of falciparum malaria and intestinal helminths co-infection among school children in Kajola, Osun state, Nigeria. METHODS: Fresh stool and blood samples were collected from 117 primary school children age range 4-15 years. The stool samples were processed using both Kato-Katz and formol-ether concentration techniques and microscopically examined for intestinal parasitic infections. Blood was collected by finger prick to determine malaria parasitemia using thick film method; and packed cell volume (PCV) was determined by hematocrit. Univariate analysis and chi-square statistical tests were used to analyze the data. RESULTS: The prevalence of Plasmodium falciparum, intestinal helminth infections, and co-infection of malaria and helminth in the study were 25.6%, 40.2% and 4.3%, respectively. Five species of intestinal helminths were recovered from the stool samples and these were Ascaris lumbricoides (34.2%), hookworm (5.1%), Trichuris trichiura (2.6%), Diphyllobothrium latum (0.9%) and Trichostrongylus species (0.9%). For the co-infection of both malaria and intestinal helminths, females (5.9%) were more infected than males (2.0%) but the difference was not statistically significant (p = 0.3978). Children who were infected with helminths were equally likely to be infected with malaria as children without intestinal helminths [Risk Ratio (RR) = 0.7295]. Children with A. lumbricoides (RR = 1.359) were also likely to be infected with P. falciparum as compared with uninfected children. CONCLUSIONS: Asymptomatic falciparum malaria and intestinal helminth infections do co-exist without clinical symp-toms in school children in Nigeria. Medknow Publications Pvt Ltd 2011-05 /pmc/articles/PMC3214381/ /pubmed/22091292 Text en Copyright: © Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ojurongbe, Olusola
Adegbayi, Adebola M
Bolaji, Oloyede S
Akindele, Akeem A
Adefioye, Olusegun A
Adeyeba, Oluwaseyi A
Asymptomatic falciparum malaria and intestinal helminths co-infection among school children in Osogbo, Nigeria
title Asymptomatic falciparum malaria and intestinal helminths co-infection among school children in Osogbo, Nigeria
title_full Asymptomatic falciparum malaria and intestinal helminths co-infection among school children in Osogbo, Nigeria
title_fullStr Asymptomatic falciparum malaria and intestinal helminths co-infection among school children in Osogbo, Nigeria
title_full_unstemmed Asymptomatic falciparum malaria and intestinal helminths co-infection among school children in Osogbo, Nigeria
title_short Asymptomatic falciparum malaria and intestinal helminths co-infection among school children in Osogbo, Nigeria
title_sort asymptomatic falciparum malaria and intestinal helminths co-infection among school children in osogbo, nigeria
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214381/
https://www.ncbi.nlm.nih.gov/pubmed/22091292
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