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Neurotoxic Effects of Tetrahydroisoquinolines and Underlying Mechanisms

Tetrahydropapaveroline (THP), a neurotoxic tetrahydroisoquinoline alkaloid formed by condensation between dopamine and dopaldehyde, has been speculated to cause Parkinson's disease and also to contribute to alcohol dependence. Having two catechol moieties, THP may readily undergo oxidation to f...

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Detalles Bibliográficos
Autores principales: Surh, Young-Joon, Kim, Hyun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214777/
https://www.ncbi.nlm.nih.gov/pubmed/22110343
http://dx.doi.org/10.5607/en.2010.19.2.63

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