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Selective Susceptibility of Human Dopaminergic Neural Stem Cells to Dopamine-Induced Apoptosis

Dysfunctions of ubiquitin-proteasome system and toxicity of dopamine have been known as the key mechanisms in the pathogenesis of Parkinson's disease (PD) and proteasome inhibitors are widely used in experimental models of PD to reproduce cell death of dopaminergic neurons. In the present study...

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Detalles Bibliográficos
Autores principales: Jeon, Sung-Man, Cheon, Sang-Myung, Bae, Hye-Rahn, Kim, Jae Woo, Kim, Seung U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214785/
https://www.ncbi.nlm.nih.gov/pubmed/22110355
http://dx.doi.org/10.5607/en.2010.19.3.155