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An in silico approach combined with in vivo experiments enables the identification of a new protein whose overexpression can compensate for specific respiratory defects in Saccharomyces cerevisiae
BACKGROUND: The mitochondrial inner membrane contains five large complexes that are essential for oxidative phosphorylation. Although the structure and the catalytic mechanisms of the respiratory complexes have been progressively established, their biogenesis is far from being fully understood. Very...
Autores principales: | Glatigny, Annie, Mathieu, Lise, Herbert, Christopher J, Dujardin, Geneviève, Meunier, Brigitte, Mucchielli-Giorgi, Marie-Hélène |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214889/ https://www.ncbi.nlm.nih.gov/pubmed/22027258 http://dx.doi.org/10.1186/1752-0509-5-173 |
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