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Probing and controlling fluorescence blinking of single semiconductor nanoparticles

In this review we present an overview of the experimental and theoretical development on fluorescence intermittency (blinking) and the roles of electron transfer in semiconductor crystalline nanoparticles. Blinking is a very interesting phenomenon commonly observed in single molecule/particle experi...

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Detalles Bibliográficos
Autores principales: Ko, Hsien-Chen, Yuan, Chi-Tsu, Tang, Jau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: CoAction Publishing 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215194/
https://www.ncbi.nlm.nih.gov/pubmed/22110871
http://dx.doi.org/10.3402/nano.v2i0.5895
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author Ko, Hsien-Chen
Yuan, Chi-Tsu
Tang, Jau
author_facet Ko, Hsien-Chen
Yuan, Chi-Tsu
Tang, Jau
author_sort Ko, Hsien-Chen
collection PubMed
description In this review we present an overview of the experimental and theoretical development on fluorescence intermittency (blinking) and the roles of electron transfer in semiconductor crystalline nanoparticles. Blinking is a very interesting phenomenon commonly observed in single molecule/particle experiments. Under continuous laser illumination, the fluorescence time trace of these single nanoparticles exhibit random light and dark periods. Since its first observation in the mid-1990s, this intriguing phenomenon has attracted wide attention among researchers from many disciplines. We will first present the historical background of the discovery and the observation of unusual inverse power-law dependence for the waiting time distributions of light and dark periods. Then, we will describe our theoretical modeling efforts to elucidate the causes for the power-law behavior, to probe the roles of electron transfer in blinking, and eventually to control blinking and to achieve complete suppression of the blinking, which is an annoying feature in many applications of quantum dots as light sources and fluorescence labels for biomedical imaging.
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spelling pubmed-32151942011-11-22 Probing and controlling fluorescence blinking of single semiconductor nanoparticles Ko, Hsien-Chen Yuan, Chi-Tsu Tang, Jau Nano Rev Review Articles In this review we present an overview of the experimental and theoretical development on fluorescence intermittency (blinking) and the roles of electron transfer in semiconductor crystalline nanoparticles. Blinking is a very interesting phenomenon commonly observed in single molecule/particle experiments. Under continuous laser illumination, the fluorescence time trace of these single nanoparticles exhibit random light and dark periods. Since its first observation in the mid-1990s, this intriguing phenomenon has attracted wide attention among researchers from many disciplines. We will first present the historical background of the discovery and the observation of unusual inverse power-law dependence for the waiting time distributions of light and dark periods. Then, we will describe our theoretical modeling efforts to elucidate the causes for the power-law behavior, to probe the roles of electron transfer in blinking, and eventually to control blinking and to achieve complete suppression of the blinking, which is an annoying feature in many applications of quantum dots as light sources and fluorescence labels for biomedical imaging. CoAction Publishing 2011-02-11 /pmc/articles/PMC3215194/ /pubmed/22110871 http://dx.doi.org/10.3402/nano.v2i0.5895 Text en © 2011 Hsien-Chen Ko et al. https://creativecommons.org/licenses/by-nc/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Articles
Ko, Hsien-Chen
Yuan, Chi-Tsu
Tang, Jau
Probing and controlling fluorescence blinking of single semiconductor nanoparticles
title Probing and controlling fluorescence blinking of single semiconductor nanoparticles
title_full Probing and controlling fluorescence blinking of single semiconductor nanoparticles
title_fullStr Probing and controlling fluorescence blinking of single semiconductor nanoparticles
title_full_unstemmed Probing and controlling fluorescence blinking of single semiconductor nanoparticles
title_short Probing and controlling fluorescence blinking of single semiconductor nanoparticles
title_sort probing and controlling fluorescence blinking of single semiconductor nanoparticles
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215194/
https://www.ncbi.nlm.nih.gov/pubmed/22110871
http://dx.doi.org/10.3402/nano.v2i0.5895
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