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Characterizing genetic interactions in human disease association studies using statistical epistasis networks

BACKGROUND: Epistasis is recognized ubiquitous in the genetic architecture of complex traits such as disease susceptibility. Experimental studies in model organisms have revealed extensive evidence of biological interactions among genes. Meanwhile, statistical and computational studies in human popu...

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Detalles Bibliográficos
Autores principales:	Hu, Ting, Sinnott-Armstrong, Nicholas A, Kiralis, Jeff W, Andrew, Angeline S, Karagas, Margaret R, Moore, Jason H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215301/ https://www.ncbi.nlm.nih.gov/pubmed/21910885 http://dx.doi.org/10.1186/1471-2105-12-364

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