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Safety, immunogenicity and preliminary efficacy of multiple-site vaccination with an Epidermal Growth Factor (EGF) based cancer vaccine in advanced non small cell lung cancer (NSCLC) patients

The prognosis of patients with advanced non small cell lung (NSCLC) cancer remains dismal. Epidermal Growth Factor Receptor is over-expressed in many epithelial derived tumors and its role in the development and progression of NSCLC is widely documented. CimaVax-EGF is a therapeutic cancer vaccine c...

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Detalles Bibliográficos
Autores principales: Rodriguez, Pedro C, Neninger, Elia, García, Beatriz, Popa, Xitlally, Viada, Carmen, Luaces, Patricia, González, Gisela, Lage, Agustin, Montero, Enrique, Crombet, Tania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215653/
https://www.ncbi.nlm.nih.gov/pubmed/22024351
http://dx.doi.org/10.1186/1476-8518-9-7