Influence of Polymorphisms in the RANKL/RANK/OPG Signaling Pathway on Volumetric Bone Mineral Density and Bone Geometry at the Forearm in Men

We sought to determine the influence of single-nucleotide polymorphisms (SNPs) in RANKL, RANK, and OPG on volumetric bone mineral density (vBMD) and bone geometry at the radius in men. Pairwise tag SNPs (r (2) ≥ 0.8) for RANKL (n = 8), RANK (n = 44), and OPG (n = 22) and five SNPs near RANKL and OPG...

Descripción completa

Detalles Bibliográficos
Autores principales: Roshandel, Delnaz, Holliday, Kate L., Pye, Stephen R., Ward, Kate A., Boonen, Steven, Vanderschueren, Dirk, Borghs, Herman, Huhtaniemi, Ilpo T., Adams, Judith E., Bartfai, Gyorgy, Casanueva, Felipe F., Finn, Joseph D., Forti, Gianni, Giwercman, Aleksander, Han, Thang S., Kula, Krzysztof, Lean, Michael E., Pendleton, Neil, Punab, Margus, Silman, Alan J., Wu, Frederick C., Thomson, Wendy, O’Neill, Terence W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215872/
https://www.ncbi.nlm.nih.gov/pubmed/21964949
http://dx.doi.org/10.1007/s00223-011-9532-y

Ejemplares similares

Ejemplares similares