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Oral administration of the K(ATP )channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis
BACKGROUND: Multiple Sclerosis (MS) is an acquired inflammatory demyelinating disorder of the central nervous system (CNS) and is the leading cause of nontraumatic disability among young adults. Activated microglial cells are important effectors of demyelination and neurodegeneration, by secreting c...
Autores principales: | Virgili, Noemí, Espinosa-Parrilla, Juan F, Mancera, Pilar, Pastén-Zamorano, Andrea, Gimeno-Bayon, Javier, Rodríguez, Manuel J, Mahy, Nicole, Pugliese, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215935/ https://www.ncbi.nlm.nih.gov/pubmed/22047130 http://dx.doi.org/10.1186/1742-2094-8-149 |
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