A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon

BACKGROUND: Chloroquine resistance (CR) decreased after the removal of chloroquine from national treatment guidelines in Malawi, Kenia and Tanzania. In this investigation the prevalence of the chloroquine resistance (CQR) conferring mutant pfcrt allele and its associated chromosomal haplotype were d...

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Detalles Bibliográficos
Autores principales: Frank, Matthias, Lehners, Nicola, Mayengue, Pembe I, Gabor, Julian, Dal-Bianco, Matthias, Kombila, David U, Ngoma, Ghyslain Mombo, Supan, Christian, Lell, Bertrand, Ntoumi, Francine, Grobusch, Martin P, Dietz, Klaus, Kremsner, Peter G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215978/
https://www.ncbi.nlm.nih.gov/pubmed/22004584
http://dx.doi.org/10.1186/1475-2875-10-304

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