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Neoadjuvant in situ gene-mediated cytotoxic immunotherapy improves postoperative outcomes in novel syngeneic esophageal carcinoma models
Esophageal carcinoma is the most rapidly increasing tumor in the United States and has a dismal 15% 5-year survival. Immunotherapy has been proposed to improve patient outcomes; however, no immunocompetent esophageal carcinoma model exists to date to test this approach. We developed two mouse models...
Autores principales: | Predina, J D, Judy, B, Aliperti, L A, Fridlender, Z G, Blouin, A, Kapoor, V, Laguna, B, Nakagawa, H, Rustgi, A K, Aguilar, L, Aguilar-Cordova, E, Albelda, S M, Singhal, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215998/ https://www.ncbi.nlm.nih.gov/pubmed/21869822 http://dx.doi.org/10.1038/cgt.2011.56 |
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