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Accelerated fracture healing in mice lacking the 5-lipoxygenase gene

BACKGROUND AND PURPOSE: Cyclooxygenase-2 (COX-2) promotes inflammation by synthesizing pro-inflammatory prostaglandins from arachidonic acid. Inflammation is an early response to bone fracture, and ablation of COX-2 activity impairs fracture healing. Arachidonic acid is also converted into leukotrie...

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Detalles Bibliográficos
Autores principales:	Manigrasso, Michaele B, O'Connor, J Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Informa Healthcare 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216088/ https://www.ncbi.nlm.nih.gov/pubmed/21067431 http://dx.doi.org/10.3109/17453674.2010.533931

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