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Beyond Diagnosis: Evolving Prostate Biopsy in the Era of Focal Therapy

Despite decades of use as the “gold standard” in the detection of prostate cancer, the optimal biopsy regimen is still not universally agreed upon. While important aspects such as the need for laterally placed biopsies and the importance of apical cancer are known, repeated studies have shown signif...

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Detalles Bibliográficos
Autores principales: Dominguez-Escrig, J. L., McCracken, S. R. C., Greene, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216124/
https://www.ncbi.nlm.nih.gov/pubmed/22110983
http://dx.doi.org/10.1155/2011/386207
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author Dominguez-Escrig, J. L.
McCracken, S. R. C.
Greene, D.
author_facet Dominguez-Escrig, J. L.
McCracken, S. R. C.
Greene, D.
author_sort Dominguez-Escrig, J. L.
collection PubMed
description Despite decades of use as the “gold standard” in the detection of prostate cancer, the optimal biopsy regimen is still not universally agreed upon. While important aspects such as the need for laterally placed biopsies and the importance of apical cancer are known, repeated studies have shown significant patients with cancer on subsequent biopsy when the original biopsy was negative and an ongoing suspicion of cancer remained. Attempts to maximise the effectiveness of repeat biopsies have given rise to the alternate approaches of saturation biopsy and the transperineal approach. Recent interest in focal treatment of prostate cancer has further highlighted the need for accurate detection of prostate cancer, and in response, the introduction of transperineal template-guided biopsy. While the saturation biopsy approach and the transperineal template approach increase the detection rate of cancer in men with a previous negative biopsy and appear to have acceptable morbidity, there is a lack of clinical trials evaluating the different biopsy strategies. This paper reviews the evolution of prostatic biopsy and current controversies.
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spelling pubmed-32161242011-11-22 Beyond Diagnosis: Evolving Prostate Biopsy in the Era of Focal Therapy Dominguez-Escrig, J. L. McCracken, S. R. C. Greene, D. Prostate Cancer Review Article Despite decades of use as the “gold standard” in the detection of prostate cancer, the optimal biopsy regimen is still not universally agreed upon. While important aspects such as the need for laterally placed biopsies and the importance of apical cancer are known, repeated studies have shown significant patients with cancer on subsequent biopsy when the original biopsy was negative and an ongoing suspicion of cancer remained. Attempts to maximise the effectiveness of repeat biopsies have given rise to the alternate approaches of saturation biopsy and the transperineal approach. Recent interest in focal treatment of prostate cancer has further highlighted the need for accurate detection of prostate cancer, and in response, the introduction of transperineal template-guided biopsy. While the saturation biopsy approach and the transperineal template approach increase the detection rate of cancer in men with a previous negative biopsy and appear to have acceptable morbidity, there is a lack of clinical trials evaluating the different biopsy strategies. This paper reviews the evolution of prostatic biopsy and current controversies. Hindawi Publishing Corporation 2011 2010-12-09 /pmc/articles/PMC3216124/ /pubmed/22110983 http://dx.doi.org/10.1155/2011/386207 Text en Copyright © 2011 J. L. Dominguez-Escrig et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Dominguez-Escrig, J. L.
McCracken, S. R. C.
Greene, D.
Beyond Diagnosis: Evolving Prostate Biopsy in the Era of Focal Therapy
title Beyond Diagnosis: Evolving Prostate Biopsy in the Era of Focal Therapy
title_full Beyond Diagnosis: Evolving Prostate Biopsy in the Era of Focal Therapy
title_fullStr Beyond Diagnosis: Evolving Prostate Biopsy in the Era of Focal Therapy
title_full_unstemmed Beyond Diagnosis: Evolving Prostate Biopsy in the Era of Focal Therapy
title_short Beyond Diagnosis: Evolving Prostate Biopsy in the Era of Focal Therapy
title_sort beyond diagnosis: evolving prostate biopsy in the era of focal therapy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216124/
https://www.ncbi.nlm.nih.gov/pubmed/22110983
http://dx.doi.org/10.1155/2011/386207
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