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Molecular Diagnostics, Targeted Therapy, and the Indication for Allogeneic Stem Cell Transplantation in Acute Lymphoblastic Leukemia

In recent years, the panel of known molecular mutations in acute lymphoblastic leukemia (ALL) has been continuously increased. In Philadelphia-positive ALL, deletions of the IKZF1 gene were identified as prognostically adverse factors. These improved insights in the molecular background and the clin...

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Detalles Bibliográficos
Autores principales: Oyekunle, Anthony, Haferlach, Torsten, Kröger, Nicolaus, Klyuchnikov, Evgeny, Zander, Axel Rolf, Schnittger, Susanne, Bacher, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216286/
https://www.ncbi.nlm.nih.gov/pubmed/22110503
http://dx.doi.org/10.1155/2011/154745