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Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration
Cell motility requires the spatial and temporal coordination of forces in the actomyosin cytoskeleton with extracellular adhesion. The biochemical mechanism that coordinates filamentous actin (F-actin) assembly, myosin contractility, adhesion dynamics, and motility to maintain the balance between ad...
Autores principales: | Delorme-Walker, Violaine D., Peterson, Jeffrey R., Chernoff, Jonathan, Waterman, Clare M., Danuser, Gaudenz, DerMardirossian, Céline, Bokoch, Gary M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216326/ https://www.ncbi.nlm.nih.gov/pubmed/21708980 http://dx.doi.org/10.1083/jcb.201010059 |
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