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The p25 subunit of the dynactin complex is required for dynein–early endosome interaction

Cytoplasmic dynein transports various cellular cargoes including early endosomes, but how dynein is linked to early endosomes is unclear. We find that the Aspergillus nidulans orthologue of the p25 subunit of dynactin is critical for dynein-mediated early endosome movement but not for dynein-mediate...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Yao, Xuanli, Fischer, Lauren, Abenza, Juan F., Peñalva, Miguel A., Xiang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216330/
https://www.ncbi.nlm.nih.gov/pubmed/21708978
http://dx.doi.org/10.1083/jcb.201011022