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Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species

Unraveling the gene regulatory networks that govern development and function of the mammalian heart is critical for the rational design of therapeutic interventions in human heart disease. Using the Drosophila heart as a platform for identifying novel gene interactions leading to heart disease, we f...

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Detalles Bibliográficos
Autores principales:	Qian, Li, Wythe, Joshua D., Liu, Jiandong, Cartry, Jerome, Vogler, Georg, Mohapatra, Bhagyalaxmi, Otway, Robyn T., Huang, Yu, King, Isabelle N., Maillet, Marjorie, Zheng, Yi, Crawley, Timothy, Taghli-Lamallem, Ouarda, Semsarian, Christopher, Dunwoodie, Sally, Winlaw, David, Harvey, Richard P., Fatkin, Diane, Towbin, Jeffrey A., Molkentin, Jeffery D., Srivastava, Deepak, Ocorr, Karen, Bruneau, Benoit G., Bodmer, Rolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216339/ https://www.ncbi.nlm.nih.gov/pubmed/21690310 http://dx.doi.org/10.1083/jcb.201006114

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