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An SNP selection strategy identified IL-22 associating with susceptibility to tuberculosis in Chinese

Recent studies showed that IL-22 plays a protective role in the host defense. However, the contribution of polymorphisms of the IL-22 gene to human TB susceptibility remains untested. We have designed a computational approach to select functional SNPs in the IL-22 gene and genotyped them in a two-st...

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Detalles Bibliográficos
Autores principales: Zhang, Guoliang, Chen, Xinchun, Chan, Long, Zhang, Mingxia, Zhu, Baohua, Wang, Lantian, Zhu, Xiuyun, Zhang, Jieyun, Zhou, Boping, Wang, Junwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216508/
https://www.ncbi.nlm.nih.gov/pubmed/22355539
http://dx.doi.org/10.1038/srep00020