Label-free integrative pharmacology on-target of drugs at the β(2)-adrenergic receptor

We describe a label-free integrative pharmacology on-target (iPOT) method to assess the pharmacology of drugs at the β(2)-adrenergic receptor. This method combines dynamic mass redistribution (DMR) assays using an array of probe molecule-hijacked cells with similarity analysis. The whole cell DMR as...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferrie, Ann M., Sun, Haiyan, Fang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216520/
https://www.ncbi.nlm.nih.gov/pubmed/22355552
http://dx.doi.org/10.1038/srep00033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216520/
https://www.ncbi.nlm.nih.gov/pubmed/22355552
http://dx.doi.org/10.1038/srep00033

Ejemplares similares