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Label-free integrative pharmacology on-target of drugs at the β(2)-adrenergic receptor

We describe a label-free integrative pharmacology on-target (iPOT) method to assess the pharmacology of drugs at the β(2)-adrenergic receptor. This method combines dynamic mass redistribution (DMR) assays using an array of probe molecule-hijacked cells with similarity analysis. The whole cell DMR as...

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Detalles Bibliográficos
Autores principales:	Ferrie, Ann M., Sun, Haiyan, Fang, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216520/ https://www.ncbi.nlm.nih.gov/pubmed/22355552 http://dx.doi.org/10.1038/srep00033

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