Specific Y14 domains mediate its nucleo-cytoplasmic shuttling and association with spliced mRNA

Pre-mRNA splicing deposits multi-protein complexes, termed exon junction complexes (EJCs), on mRNAs near exon-exon junctions. The core of EJC consists of four proteins, eIF4AIII, MLN51, Y14 and Magoh. Y14 is a nuclear protein that can shuttle between the nucleus and the cytoplasm, and binds specific...

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Detalles Bibliográficos
Autores principales: Kataoka, Naoyuki, Diem, Michael D., Yoshida, Mayumi, Hatai, Chihiro, Dobashi, Izumi, Dreyfuss, Gideon, Hagiwara, Masatoshi, Ohno, Mutsuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216578/
https://www.ncbi.nlm.nih.gov/pubmed/22355610
http://dx.doi.org/10.1038/srep00092

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