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Huntingtin mediates dendritic transport of β-actin mRNA in rat neurons
Transport of mRNAs to diverse neuronal locations via RNA granules serves an important function in regulating protein synthesis within restricted sub-cellular domains. We recently detected the Huntington's disease protein huntingtin (Htt) in dendritic RNA granules; however, the functional signif...
Autores principales: | Ma, Bin, Savas, Jeffrey N., Yu, Man-Shan, Culver, Brady P., Chao, Moses V., Tanese, Naoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216621/ https://www.ncbi.nlm.nih.gov/pubmed/22355657 http://dx.doi.org/10.1038/srep00140 |
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