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Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse

Diacylglycerol (DAG) generation at the T cell immunological synapse (IS) determines the correct activation of antigen-specific immune responses. DAG kinases (DGKs) α and ζ act as negative regulators of DAG-mediated signals by catalyzing DAG conversion to phosphatidic acid (PA). Nonetheless, the spec...

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Detalles Bibliográficos
Autores principales:	Gharbi, Severine I., Rincón, Esther, Avila-Flores, Antonia, Torres-Ayuso, Pedro, Almena, María, Cobos, María Angeles, Albar, Juan Pablo, Mérida, Isabel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216665/ https://www.ncbi.nlm.nih.gov/pubmed/21937721 http://dx.doi.org/10.1091/mbc.E11-03-0247

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