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Splice isoform estrogen receptors as integral transmembrane proteins

In addition to enhancing or repressing transcription, steroid hormone receptors rapidly transduce kinase activation signals. On ligand engagement, an N-terminus–truncated splice isoform of estrogen receptor (ER) α, ER46, triggers membrane-initiated signals, resulting in endothelial nitric oxide synt...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Hee, Toomre, Derek, Bender, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216666/
https://www.ncbi.nlm.nih.gov/pubmed/21937726
http://dx.doi.org/10.1091/mbc.E11-05-0416