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NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II
The vasoactive peptide urotensin-II (U-II) has been associated with vascular remodeling in different cardiovascular disorders. Although U-II can induce reactive oxygen species (ROS) by the NADPH oxidase NOX4 and stimulate smooth muscle cell (SMC) proliferation, the precise mechanisms linking U-II to...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216667/ https://www.ncbi.nlm.nih.gov/pubmed/21965295 http://dx.doi.org/10.1091/mbc.E10-12-0971 |