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NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II

The vasoactive peptide urotensin-II (U-II) has been associated with vascular remodeling in different cardiovascular disorders. Although U-II can induce reactive oxygen species (ROS) by the NADPH oxidase NOX4 and stimulate smooth muscle cell (SMC) proliferation, the precise mechanisms linking U-II to...

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Detalles Bibliográficos
Autores principales: Diebold, Isabel, Petry, Andreas, Burger, Maximilian, Hess, John, Görlach, Agnes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216667/
https://www.ncbi.nlm.nih.gov/pubmed/21965295
http://dx.doi.org/10.1091/mbc.E10-12-0971

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