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Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa

BACKGROUND: Despite their well-established functional roles, histone modifications have received less attention than DNA methylation in the cancer field. In order to evaluate their importance in colorectal cancer (CRC), we generated the first genome-wide histone modification profiles in paired norma...

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Detalles Bibliográficos
Autores principales: Enroth, Stefan, Rada-Iglesisas, Alvaro, Andersson, Robin, Wallerman, Ola, Wanders, Alkwin, Påhlman, Lars, Komorowski, Jan, Wadelius, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216894/
https://www.ncbi.nlm.nih.gov/pubmed/22011431
http://dx.doi.org/10.1186/1471-2407-11-450