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Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa
BACKGROUND: Despite their well-established functional roles, histone modifications have received less attention than DNA methylation in the cancer field. In order to evaluate their importance in colorectal cancer (CRC), we generated the first genome-wide histone modification profiles in paired norma...
Autores principales: | Enroth, Stefan, Rada-Iglesisas, Alvaro, Andersson, Robin, Wallerman, Ola, Wanders, Alkwin, Påhlman, Lars, Komorowski, Jan, Wadelius, Claes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216894/ https://www.ncbi.nlm.nih.gov/pubmed/22011431 http://dx.doi.org/10.1186/1471-2407-11-450 |
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