Ebola Virus Glycoprotein Needs an Additional Trigger, beyond Proteolytic Priming for Membrane Fusion

BACKGROUND: Ebolavirus belongs to the family filoviridae and causes severe hemorrhagic fever in humans with 50–90% lethality. Detailed understanding of how the viruses attach to and enter new host cells is critical to development of medical interventions. The virus displays a trimeric glycoprotein (...

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Detalles Bibliográficos
Autores principales: Bale, Shridhar, Liu, Tong, Li, Sheng, Wang, Yuhao, Abelson, Dafna, Fusco, Marnie, Woods, Virgil L., Ollmann Saphire, Erica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216919/
https://www.ncbi.nlm.nih.gov/pubmed/22102923
http://dx.doi.org/10.1371/journal.pntd.0001395

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