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Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors

BACKGROUND: The human placenta facilitates the exchange of nutrients, gas and waste between the fetal and maternal circulations. It also protects the fetus from the maternal immune response. Due to its role at the feto-maternal interface, the placenta is subject to many environmental exposures that...

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Detalles Bibliográficos
Autores principales: Novakovic, Boris, Yuen, Ryan K, Gordon, Lavinia, Penaherrera, Maria S, Sharkey, Andrew, Moffett, Ashley, Craig, Jeffrey M, Robinson, Wendy P, Saffery, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216976/
https://www.ncbi.nlm.nih.gov/pubmed/22032438
http://dx.doi.org/10.1186/1471-2164-12-529