Enhancement of Canonical Wnt/β-Catenin Signaling Activity by HCV Core Protein Promotes Cell Growth of Hepatocellular Carcinoma Cells

BACKGROUND: The Hepatitis C virus (HCV) core protein has been implicated as a potential oncogene or a cofactor in HCV-related hepatocellular carcinoma (HCC), but the underlying mechanisms are unknown. Overactivation of the Wnt/β-catenin signaling is a major factor in oncogenesis of HCC. However, the...

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Detalles Bibliográficos
Autores principales: Liu, Jiao, Ding, Xiong, Tang, Jia, Cao, Youde, Hu, Peng, Zhou, Fan, Shan, Xiaoliang, Cai, Xuefei, Chen, Qingmei, Ling, Ning, Zhang, Bingqiang, Bi, Yang, Chen, Ke, Ren, Hong, Huang, Ailong, He, Tong-Chuan, Tang, Ni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216985/
https://www.ncbi.nlm.nih.gov/pubmed/22110662
http://dx.doi.org/10.1371/journal.pone.0027496

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