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A case study for efficient management of high throughput primary lab data

BACKGROUND: In modern life science research it is very important to have an efficient management of high throughput primary lab data. To realise such an efficient management, four main aspects have to be handled: (I) long term storage, (II) security, (III) upload and (IV) retrieval. FINDINGS: In thi...

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Autores principales: Colmsee, Christian, Flemming, Steffen, Klapperstück, Matthias, Lange, Matthias, Scholz, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217054/
https://www.ncbi.nlm.nih.gov/pubmed/22005096
http://dx.doi.org/10.1186/1756-0500-4-413
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author Colmsee, Christian
Flemming, Steffen
Klapperstück, Matthias
Lange, Matthias
Scholz, Uwe
author_facet Colmsee, Christian
Flemming, Steffen
Klapperstück, Matthias
Lange, Matthias
Scholz, Uwe
author_sort Colmsee, Christian
collection PubMed
description BACKGROUND: In modern life science research it is very important to have an efficient management of high throughput primary lab data. To realise such an efficient management, four main aspects have to be handled: (I) long term storage, (II) security, (III) upload and (IV) retrieval. FINDINGS: In this paper we define central requirements for a primary lab data management and discuss aspects of best practices to realise these requirements. As a proof of concept, we introduce a pipeline that has been implemented in order to manage primary lab data at the Leibniz Institute of Plant Genetics and Crop Plant Research (IPK). It comprises: (I) a data storage implementation including a Hierarchical Storage Management system, a relational Oracle Database Management System and a BFiler package to store primary lab data and their meta information, (II) the Virtual Private Database (VPD) implementation for the realisation of data security and the LIMS Light application to (III) upload and (IV) retrieve stored primary lab data. CONCLUSIONS: With the LIMS Light system we have developed a primary data management system which provides an efficient storage system with a Hierarchical Storage Management System and an Oracle relational database. With our VPD Access Control Method we can guarantee the security of the stored primary data. Furthermore the system provides high performance upload and download and efficient retrieval of data.
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spelling pubmed-32170542011-11-16 A case study for efficient management of high throughput primary lab data Colmsee, Christian Flemming, Steffen Klapperstück, Matthias Lange, Matthias Scholz, Uwe BMC Res Notes Technical Note BACKGROUND: In modern life science research it is very important to have an efficient management of high throughput primary lab data. To realise such an efficient management, four main aspects have to be handled: (I) long term storage, (II) security, (III) upload and (IV) retrieval. FINDINGS: In this paper we define central requirements for a primary lab data management and discuss aspects of best practices to realise these requirements. As a proof of concept, we introduce a pipeline that has been implemented in order to manage primary lab data at the Leibniz Institute of Plant Genetics and Crop Plant Research (IPK). It comprises: (I) a data storage implementation including a Hierarchical Storage Management system, a relational Oracle Database Management System and a BFiler package to store primary lab data and their meta information, (II) the Virtual Private Database (VPD) implementation for the realisation of data security and the LIMS Light application to (III) upload and (IV) retrieve stored primary lab data. CONCLUSIONS: With the LIMS Light system we have developed a primary data management system which provides an efficient storage system with a Hierarchical Storage Management System and an Oracle relational database. With our VPD Access Control Method we can guarantee the security of the stored primary data. Furthermore the system provides high performance upload and download and efficient retrieval of data. BioMed Central 2011-10-17 /pmc/articles/PMC3217054/ /pubmed/22005096 http://dx.doi.org/10.1186/1756-0500-4-413 Text en Copyright ©2011 Colmsee et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Technical Note
Colmsee, Christian
Flemming, Steffen
Klapperstück, Matthias
Lange, Matthias
Scholz, Uwe
A case study for efficient management of high throughput primary lab data
title A case study for efficient management of high throughput primary lab data
title_full A case study for efficient management of high throughput primary lab data
title_fullStr A case study for efficient management of high throughput primary lab data
title_full_unstemmed A case study for efficient management of high throughput primary lab data
title_short A case study for efficient management of high throughput primary lab data
title_sort case study for efficient management of high throughput primary lab data
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217054/
https://www.ncbi.nlm.nih.gov/pubmed/22005096
http://dx.doi.org/10.1186/1756-0500-4-413
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