Genome wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget’s disease of bone

Paget’s disease of bone (PDB) is a common disorder with a strong genetic component characterised by focal increases in bone turnover which in some cases is caused by SQSTM1 mutations. To identify additional susceptibility genes we performed a genome wide association study in 750 PDB cases without SQ...

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Detalles Bibliográficos
Autores principales: Albagha, Omar ME, Visconti, Micaela R, Alonso, Nerea, Langston, Anne L, Cundy, Tim, Dargie, Rosemary, Dunlop, Malcolm G, Fraser, William D, Hooper, Michael J, Isaia, Gianluca, Nicholson, Geoff C, del Pino Montes, Javier, Gonzalez-Sarmiento, Rogelio, di Stefano, Marco, Tenesa, Albert, Walsh, John P, Ralston, Stuart H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217192/
https://www.ncbi.nlm.nih.gov/pubmed/20436471
http://dx.doi.org/10.1038/ng.562

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