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GSK-3 Mouse Models to Study Neuronal Apoptosis and Neurodegeneration

Increased GSK-3 activity is believed to contribute to the etiology of chronic disorders like Alzheimer’s disease (AD), schizophrenia, diabetes, and some types of cancer, thus supporting therapeutic potential of GSK-3 inhibitors. Numerous mouse models with modified GSK-3 have been generated in order...

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Detalles Bibliográficos
Autores principales:	Gómez-Sintes, Raquel, Hernández, Félix, Lucas, José J., Avila, Jesús
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217194/ https://www.ncbi.nlm.nih.gov/pubmed/22110426 http://dx.doi.org/10.3389/fnmol.2011.00045

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