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Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines
The synthesis of several (2-oxaadamant-1-yl)amines is reported. They were evaluated as NMDA receptor antagonists and several of them were more active than amantadine, but none was more potent than memantine. None of the tested compounds displayed antiviral activity. Two of the derivatives showed a s...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd. Published by Elsevier Ltd.
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217223/ https://www.ncbi.nlm.nih.gov/pubmed/19251424 http://dx.doi.org/10.1016/j.bmc.2009.02.007 |