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A Showcase of Bench-to-Bedside Regenerative Medicine at the 2010 ASNTR

Insight into the expanding themes of regenerative medicine is provided by the American Society for Neural Therapy and Repair's annual meeting. The 17th meeting covered a wide range of neurodegenerative disorders, exploring methods to elucidate the currently unknown mechanisms behind the disorde...

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Detalles Bibliográficos
Autores principales: Eve, David J., Borlongan, Cesar V., Sanberg, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217594/
https://www.ncbi.nlm.nih.gov/pubmed/22125442
http://dx.doi.org/10.1100/2011/341532
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author Eve, David J.
Borlongan, Cesar V.
Sanberg, Paul R.
author_facet Eve, David J.
Borlongan, Cesar V.
Sanberg, Paul R.
author_sort Eve, David J.
collection PubMed
description Insight into the expanding themes of regenerative medicine is provided by the American Society for Neural Therapy and Repair's annual meeting. The 17th meeting covered a wide range of neurodegenerative disorders, exploring methods to elucidate the currently unknown mechanisms behind the disorders, as well as possible treatments ranging from the use of growth factors, gene therapy to cell transplantation. The importance of growth factors, both as a contributing factor to a disease and as a possible treatment either solo, or as a consequence of, or in conjunction with, stem cell therapy, was highlighted. The potential for viral vectors was also explored either for cells prior to transplantation or as a direct treatment regime into the brain itself. Identification of biomarkers that would allow early detection of a disease is an important factor in our fight against disease. The ability to now perform whole genome analysis and biomolecular profiling provides hope that such markers could be identified which not only could identify this likely to suffer from a disorder but also could allow its progress to be monitored. A few preclinical and clinical cell transplantation trials were also introduced as potential areas of followup in the years to come.
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spelling pubmed-32175942011-11-28 A Showcase of Bench-to-Bedside Regenerative Medicine at the 2010 ASNTR Eve, David J. Borlongan, Cesar V. Sanberg, Paul R. ScientificWorldJournal Review Article Insight into the expanding themes of regenerative medicine is provided by the American Society for Neural Therapy and Repair's annual meeting. The 17th meeting covered a wide range of neurodegenerative disorders, exploring methods to elucidate the currently unknown mechanisms behind the disorders, as well as possible treatments ranging from the use of growth factors, gene therapy to cell transplantation. The importance of growth factors, both as a contributing factor to a disease and as a possible treatment either solo, or as a consequence of, or in conjunction with, stem cell therapy, was highlighted. The potential for viral vectors was also explored either for cells prior to transplantation or as a direct treatment regime into the brain itself. Identification of biomarkers that would allow early detection of a disease is an important factor in our fight against disease. The ability to now perform whole genome analysis and biomolecular profiling provides hope that such markers could be identified which not only could identify this likely to suffer from a disorder but also could allow its progress to be monitored. A few preclinical and clinical cell transplantation trials were also introduced as potential areas of followup in the years to come. TheScientificWorldJOURNAL 2011-10-23 /pmc/articles/PMC3217594/ /pubmed/22125442 http://dx.doi.org/10.1100/2011/341532 Text en Copyright © 2011 David J. Eve et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Eve, David J.
Borlongan, Cesar V.
Sanberg, Paul R.
A Showcase of Bench-to-Bedside Regenerative Medicine at the 2010 ASNTR
title A Showcase of Bench-to-Bedside Regenerative Medicine at the 2010 ASNTR
title_full A Showcase of Bench-to-Bedside Regenerative Medicine at the 2010 ASNTR
title_fullStr A Showcase of Bench-to-Bedside Regenerative Medicine at the 2010 ASNTR
title_full_unstemmed A Showcase of Bench-to-Bedside Regenerative Medicine at the 2010 ASNTR
title_short A Showcase of Bench-to-Bedside Regenerative Medicine at the 2010 ASNTR
title_sort showcase of bench-to-bedside regenerative medicine at the 2010 asntr
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217594/
https://www.ncbi.nlm.nih.gov/pubmed/22125442
http://dx.doi.org/10.1100/2011/341532
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