TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model

BACKGROUND: The T-box transcription factor TBX3 is necessary for early embryonic development and for the normal development of the mammary gland. Homozygous mutations, in mice, are embryonic lethal while heterozygous mutations result in perturbed mammary gland development. In humans, mutations that...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Esmailpour, Taraneh, Shang, Xiying, Gulsen, Gultekin, Liu, Andy, Huang, Taosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217876/
https://www.ncbi.nlm.nih.gov/pubmed/22039763
http://dx.doi.org/10.1186/1471-213X-11-65

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