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Arthrogenicity of type II collagen monoclonal antibodies associated with complement activation and antigen affinity

BACKGROUND: The collagen antibody-induced arthritis (CAIA) model, which employs a cocktail of monoclonal antibodies (mAbs) to type II collagen (CII), has been widely used for studying the pathogenesis of autoimmune arthritis. In this model, not all mAbs to CII are capable of inducing arthritis becau...

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Detalles Bibliográficos
Autores principales:	Koobkokkruad, Thongchai, Kadotani, Tatsuya, Hutamekalin, Pilaiwanwadee, Mizutani, Nobuaki, Yoshino, Shin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217917/ https://www.ncbi.nlm.nih.gov/pubmed/22054174 http://dx.doi.org/10.1186/1476-9255-8-31

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