Cargando…
Regulatory T Cells and IL-10 Independently Counterregulate Cytotoxic T Lymphocyte Responses Induced by Transcutaneous Immunization
BACKGROUND: The imidazoquinoline derivate imiquimod induces inflammatory responses and protection against transplanted tumors when applied to the skin in combination with a cognate peptide epitope (transcutaneous immunization, TCI). Here we investigated the role of regulatory T cells (T(reg)) and th...
Autores principales: | Stein, Pamela, Weber, Michael, Prüfer, Steve, Schmid, Beate, Schmitt, Edgar, Probst, Hans-Christian, Waisman, Ari, Langguth, Peter, Schild, Hansjörg, Radsak, Markus P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218067/ https://www.ncbi.nlm.nih.gov/pubmed/22114725 http://dx.doi.org/10.1371/journal.pone.0027911 |
Ejemplares similares
-
Efficacy of Imiquimod-Based Transcutaneous Immunization Using a Nano-Dispersed Emulsion Gel Formulation
por: Stein, Pamela, et al.
Publicado: (2014) -
Optimized dithranol-imiquimod-based transcutaneous immunization enables tumor rejection
por: Hartmann, Ann-Kathrin, et al.
Publicado: (2023) -
Mechanisms of Cyclic Nucleotide Phosphodiesterases in Modulating T Cell Responses in Murine Graft-versus-Host Disease
por: Weber, Michael, et al.
Publicado: (2013) -
Evaluation and Validation of the Detection of soluble Triggering Receptor Expressed on Myeloid Cells 1 by Enzyme-linked immunosorbent Assay
por: Hasibeder, Astrid, et al.
Publicado: (2015) -
CD27 expression on Treg cells limits immune responses against tumors
por: Muth, Sabine, et al.
Publicado: (2021)