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Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells

BACKGROUND: N-(4-hydroxyphenyl)retinamide (4-HPR, fenretinide) is a synthetic retinoid with potent pro-apoptotic activity against several types of cancer, but little is known regarding mechanisms leading to chemoresistance. Ceramide and, more recently, other sphingolipid species (e.g., dihydrocerami...

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Detalles Bibliográficos
Autores principales:	Apraiz, Aintzane, Idkowiak-Baldys, Jolanta K, Boyano, María Dolores, Pérez-Yarza, Gorka, Hannun, Yusuf A, Asumendi, Aintzane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218121/ https://www.ncbi.nlm.nih.gov/pubmed/22061047 http://dx.doi.org/10.1186/1471-2407-11-477

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