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Tyrosinase Small Interfering RNA Effectively Suppresses Tyrosinase Gene Expression In Vitro and In Vivo

Tyrosinase is a bifunctional enzyme which oxidizes the initial step of melanin biosynthesis, that is, conversion of tyrosine to dopa and subsequently dopa to dopaquinone. It is a glycosylated protein and a major regulator of melanogenesis. To date, many approaches have been tried to regulate tyrosin...

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Detalles Bibliográficos
Autores principales: Xiu-Hua, Jia, Shao-Chun, Lin, Bing, Huang, Xiang, Zhu, Jing, Zhuang, Wei-Hua, Li, Qian, Liu, Ting, Luo, Xiao-Ping, Xu, Xi-Gu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218303/
https://www.ncbi.nlm.nih.gov/pubmed/22110954
http://dx.doi.org/10.4061/2010/240472