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Virtual screening of 2,3-disubstituted-4(3H)-quinazolinones possessing benzenesulfonamide moiety for COX-2 inhibitor

COX inhibitors which selectively inhibits the inducible COX-2 is an oenzyme that causes inflammation. They are clinically effective anti-inflammatory agents with less gastrointestinal and renal toxicity. However, they lack anti-thrombotic activity and hence lead to increased incidences of adverse ca...

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Detalles Bibliográficos
Autores principales:	Hayun, Yanuar, Arry, Hanafi, Muhammad, PWS, Sumi Hudiyono
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2011
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218419/ https://www.ncbi.nlm.nih.gov/pubmed/22125393

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