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Preparation of polylactide-co-glycolide nanoparticles incorporating celecoxib and their antitumor activity against brain tumor cells
BACKGROUND: Celecoxib, a cyclo-oxygenase (COX)-2 inhibitor, has been reported to mediate growth inhibitory effects and to induce apoptosis in various cancer cell lines. In this study, we examined the potential effects of celecoxib on glioma cell proliferation, migration, and inhibition of COX-2 expr...
Autores principales: | Kim, Tae-Ho, Jeong, Young-Il, Jin, Shu-Guang, Pei, Jian, Jung, Tae-Young, Moon, Kyung-Sub, Kim, In-Young, Kang, Sam-Suk, Jung, Shin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218576/ https://www.ncbi.nlm.nih.gov/pubmed/22114493 http://dx.doi.org/10.2147/IJN.S19497 |
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