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Novel docetaxel-loaded nanoparticles based on PCL-Tween 80 copolymer for cancer treatment
BACKGROUND: The formulation of docetaxel available for clinical use (Taxotere(®)) contains a high concentration of polysorbate 80 (Tween 80). After incorporation of Tween 80 into poly-ɛ-caprolactone (PCL)-Tween 80 copolymer, the relative amount of Tween 80 should be decreased and the advantages of P...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218581/ https://www.ncbi.nlm.nih.gov/pubmed/22114498 http://dx.doi.org/10.2147/IJN.S25251 |