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Emerging therapies for treatment of multiple sclerosis

In the last decade, a new armamentarium of immune-based therapies have been developed and tested in patients with multiple sclerosis. Some of these therapies are showing a high level of efficacy, with an acceptable adverse effect profile. Because present therapies have significant limitations in slo...

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Detalles Bibliográficos
Autores principales: Corboy, John R, Miravalle, Augusto A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218736/
https://www.ncbi.nlm.nih.gov/pubmed/22096357
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author Corboy, John R
Miravalle, Augusto A
author_facet Corboy, John R
Miravalle, Augusto A
author_sort Corboy, John R
collection PubMed
description In the last decade, a new armamentarium of immune-based therapies have been developed and tested in patients with multiple sclerosis. Some of these therapies are showing a high level of efficacy, with an acceptable adverse effect profile. Because present therapies have significant limitations in slowing disease progression, require injections, are sometimes associated with significant side effects of immunosuppression, and do little to reverse disability, identifying more effective treatments is an important goal for clinical research in multiple sclerosis. However, in order to improve our current approach to disease-modifying therapies, it is imperative to promote the development of individualized therapy strategies.
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spelling pubmed-32187362011-11-17 Emerging therapies for treatment of multiple sclerosis Corboy, John R Miravalle, Augusto A J Inflamm Res Review In the last decade, a new armamentarium of immune-based therapies have been developed and tested in patients with multiple sclerosis. Some of these therapies are showing a high level of efficacy, with an acceptable adverse effect profile. Because present therapies have significant limitations in slowing disease progression, require injections, are sometimes associated with significant side effects of immunosuppression, and do little to reverse disability, identifying more effective treatments is an important goal for clinical research in multiple sclerosis. However, in order to improve our current approach to disease-modifying therapies, it is imperative to promote the development of individualized therapy strategies. Dove Medical Press 2010-07-23 /pmc/articles/PMC3218736/ /pubmed/22096357 Text en © 2010 Corboy and Miravalle, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Corboy, John R
Miravalle, Augusto A
Emerging therapies for treatment of multiple sclerosis
title Emerging therapies for treatment of multiple sclerosis
title_full Emerging therapies for treatment of multiple sclerosis
title_fullStr Emerging therapies for treatment of multiple sclerosis
title_full_unstemmed Emerging therapies for treatment of multiple sclerosis
title_short Emerging therapies for treatment of multiple sclerosis
title_sort emerging therapies for treatment of multiple sclerosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218736/
https://www.ncbi.nlm.nih.gov/pubmed/22096357
work_keys_str_mv AT corboyjohnr emergingtherapiesfortreatmentofmultiplesclerosis
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