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Effects of SU5416 and a vascular endothelial growth factor neutralizing antibody on wear debris-induced inflammatory osteolysis in a mouse model
BACKGROUND: The development of highly vascularized and inflammatory periprosthetic tissue characterizes the progress of aseptic loosening, a major complication of joint arthroplasty. Vascular endothelial growth factor (VEGF) is an important cell signaling protein involved in angiogenesis. The purpos...
Autores principales: | Ren, Weiping, Zhang, Renwen, Wu, Bin, Wooley, Paul H, Hawkins, Monica, Markel, David C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218747/ https://www.ncbi.nlm.nih.gov/pubmed/22096367 http://dx.doi.org/10.2147/JIR.S16232 |
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