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5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells

BACKGROUND: 5-Hydroxymethylcytosine (5hmC) was recently found to be abundantly present in certain cell types, including embryonic stem cells. There is growing evidence that TET proteins, which convert 5-methylcytosine (5mC) to 5hmC, play important biological roles. To further understand the function...

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Detalles Bibliográficos
Autores principales: Stroud, Hume, Feng, Suhua, Morey Kinney, Shannon, Pradhan, Sriharsa, Jacobsen, Steven E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218842/
https://www.ncbi.nlm.nih.gov/pubmed/21689397
http://dx.doi.org/10.1186/gb-2011-12-6-r54

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