High recombination rates and hotspots in a Plasmodium falciparum genetic cross

BACKGROUND: The human malaria parasite Plasmodium falciparum survives pressures from the host immune system and antimalarial drugs by modifying its genome. Genetic recombination and nucleotide substitution are the two major mechanisms that the parasite employs to generate genome diversity. A better...

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Detalles Bibliográficos
Autores principales: Jiang, Hongying, Li, Na, Gopalan, Vivek, Zilversmit, Martine M, Varma, Sudhir, Nagarajan, Vijayaraj, Li, Jian, Mu, Jianbing, Hayton, Karen, Henschen, Bruce, Yi, Ming, Stephens, Robert, McVean, Gilean, Awadalla, Philip, Wellems, Thomas E, Su, Xin-zhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218859/
https://www.ncbi.nlm.nih.gov/pubmed/21463505
http://dx.doi.org/10.1186/gb-2011-12-4-r33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218859/
https://www.ncbi.nlm.nih.gov/pubmed/21463505
http://dx.doi.org/10.1186/gb-2011-12-4-r33

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