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Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells

INTRODUCTION: Notochordal cells (NCs) are influential in development of the intervertebral disc (IVD) and species that retain NCs do not degenerate. IVD repair using bone marrow derived mesenchymal stem cells (MSCs) is an attractive approach and the harsh microenvironment of the IVD suggests pre-dif...

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Detalles Bibliográficos
Autores principales:	Purmessur, Devina, Schek, Rachel M, Abbott, Rosalyn D, Ballif, Bryan A, Godburn, Karolyn E, Iatridis, James C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218891/ https://www.ncbi.nlm.nih.gov/pubmed/21627827 http://dx.doi.org/10.1186/ar3344

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