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The SLC2A9 nonsynonymous Arg265His variant and gout: evidence for a population-specific effect on severity

INTRODUCTION: The C allele of the nonsynonymous Arg265His (rs3733591) variant of SLC2A9 confers risk for gout in Han Chinese, Solomon Island and Japanese samples, with a stronger role in tophaceous gout. There is no evidence for an association with gout in Caucasian populations. In the present study...

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Detalles Bibliográficos
Autores principales: Hollis-Moffatt, Jade E, Gow, Peter J, Harrison, Andrew A, Highton, John, Jones, Peter BB, Stamp, Lisa K, Dalbeth, Nicola, Merriman, Tony R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218899/
https://www.ncbi.nlm.nih.gov/pubmed/21658257
http://dx.doi.org/10.1186/ar3356

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